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GTIN vs UPC, EAN, and ISBN: The Complete Guide for Amazon Sellers in 2025

Free Guide

GTIN vs UPC, EAN, and ISBN: The Complete Guide for Amazon Sellers in 2025

Lab 916 Team

January 21, 2026

10 min read

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GTIN vs UPC, EAN, and ISBN: The Complete Guide for Amazon Sellers in 2025

After selling on Amazon for some time, you'll notice that being competitive isn't enough. You need strategic promotional tactics to stand out. That's where Amazon Lightning Deals become essential. When executed properly with expert Amazon advertising strategy, Lightning Deals can drive rapid sales growth and significantly boost your product visibility on Today's Deals page.


A GTIN (Global Trade Item Number) is a unique product identifier code embedded within a barcode that's required to sell items in stores or on e-commerce platforms like Amazon. These identification numbers help you manage inventory and ensure each product is uniquely identifiable in the global marketplace.

The Key Insight:
Technically, there is no difference between a GTIN vs UPC because they are one and the same. Likewise, UPC, EAN, and ISBN are all GTINs. That's because a GTIN is the number encoded into either a UPC, EAN, or ISBN barcode.


In this comprehensive 2025 guide, we'll clarify the relationship between GTIN vs UPC, explain what makes up each identifier type, show you how to purchase them, and cover how Amazon's FNSKU ties into the barcode system. Whether you're launching your first product or expanding to international markets, this guide provides everything you need to know about product identifiers.

GS1 Membership Costs in 2025


The cost of purchasing GTINs for your product line depends on how many you need, referred to as "Prefix Capacity." In 2025, GS1 continues to offer flexible pricing tiers for businesses of all sizes.

Initial Membership Fees


Number of Products

Initial Fee (2025)

1-10 products

$30 (one-time, single GTIN)

10 products

$250

100 products

$750

1,000 products

$2,500

10,000 products

$6,500

Annual Renewal Fees


GTINs are licensed on an annual basis. You must renew your license each year to keep your barcodes valid. The renewal fee is typically 50% of your initial membership cost.

Cost-Saving Tip:

If you're launching multiple products, it's more cost-effective to purchase a larger capacity upfront. Upgrading later requires additional fees. Calculate your 2-3 year product roadmap before selecting your tier.


What's the Difference Between GTIN and FNSKU?


FNSKU stands for Fulfillment Network Stock Keeping Unit, which is Amazon-specific. An FNSKU is automatically generated when you create a product listing in Amazon Seller Central and needs to be visibly labeled on your product when shipping to Amazon fulfillment centers.,,

Just like a GTIN, an FNSKU is a unique set of numbers connected to a specific barcode for a product. However, there's a key difference in when you need each type:


When to Use GTIN/UPC
  • Creating your product listing

  • Selling products you manufacture

  • Brand-registered products

  • Multi-channel selling (Amazon + retail)

  • 15%+ discount from reference price

  • No active coupons or promotions

  • Clean account health (ODR < 1%)


When to Use FNSKU
  • Multiple sellers offer the same product

  • Using Amazon FBA services

  • Reselling branded products

  • Inventory tracking at Amazon warehouses

Amazon FBA Best Practice:

FNSKUs are essential when selling on Amazon if you're using FBA and multiple sellers offer the same product. The FNSKU identifies both the product AND the seller to Amazon's fulfillment staff.

This way, if an item is determined to be counterfeit or unsellable, Amazon can identify which seller is responsible. If you sell a branded item that no one else sells on Amazon, you can use your UPC/EAN directly without needing FNSKU labels.


Key Takeaways for 2025


GTIN barcode numbers, such as UPC and EAN, are essential data structures that help businesses worldwide maintain and manage their product catalogs efficiently. Understanding these identifiers is crucial for success on Amazon and other e-commerce platforms.


Remember This

Don't overthink GTIN vs UPC vs EAN—they're interchangeable for most purposes

Buy from GS1

Always purchase from official sources to avoid invalid codes

Plan Ahead

Calculate 2-3 year product needs before choosing capacity

Know When to Use FNSKU

Required for FBA when multiple sellers offer same product


Now that you've mastered GTIN fundamentals, you're ready to set up your product listings correctly. For more guidance on launching successfully on Amazon, explore our comprehensive Amazon seller guides or check out our latest Amazon insights.

Complete Amazon Launch Services

Beyond GTIN setup, we offer comprehensive Amazon launch services:

Complete Amazon Launch Services

Beyond GTIN setup, we offer comprehensive Amazon launch services: